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Friday Seminar by Ms. Rinchuila shimphrui

AG Lab/ Friday/May 3, 2019/ 3.30 pm/ Epigenetic regulation orchestrates thermomemory in Arabidopsis thaliana
Category: Research
Posted by: bedineel



Epigenetic regulation orchestrates thermomemory in Arabidopsis thaliana


High temperature disrupts plant growth and metabolism. Plants have evolved several genetic as well as epigenetic machineries, which enhances the heat stress tolerance. Tolerance to lethal heat stress is established through molecular stress memory of previous exposures to mild or severe transient stress. Thermomemory allows plants for a quick and robust response to future stress. However, thermomemory is proxy alternative rather than a rule. Several machineries including chromatin remodellers and siRNA pathways inhibit the transgenerational transmission of heat induced epigenetic states. Nonetheless, recent studies have shown that certain plants exhibit transgenerational memory in one or two subsequent, non-stressed progeny plants. Investigations on these plants show that a positive feedback loop between HSFA2 and H3K27me3 demethylase plays a crucial role in transmitting long-term epigenetic thermomemory through reduced H3K27me3 and siRNA biogenesis. Furthermore, glucose based-thermomemory finds its importance by the promotion of H3K4 trimethylation mediated through HLP1 gene. These findings reveal the profound role of epigenetic regulation of thermomemory.




Liu, J., Feng, L., Gu, X., Deng, X., Qiu, Q., Li, Q., ... & He, Y. (2019). An H3K27me3 demethylase-HSFA2 regulatory loop orchestrates transgenerational thermomemory in Arabidopsis. Cell research, 1.


Sharma, M., Banday, Z. Z., Shukla, B. N., & Laxmi, A. (2019). Glucose-regulated HLP1 acts as a key molecule in governing thermomemory. Plant physiology, pp-01371.